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Hyun Sun Lee Selected Research

Diacylglycerol O-Acyltransferase

11/2014Therapeutic strategies for metabolic diseases: Small-molecule diacylglycerol acyltransferase (DGAT) inhibitors.
1/2014Discovery of a novel class of diacylglycerol acyltransferase 2 inhibitors with a 1H-pyrrolo[2,3-b]pyridine core.
7/2011Isolation of diacyl glycerol acyl transferase (DGAT) inhibitors from Pachydictyon coriaceum.
1/2009Diacylglycerol acyltransferase-inhibitory compounds from Erythrina senegalensis.
11/2008Sesquiterpenoids isolated from the flower buds of Tussilago farfara L. inhibit diacylglycerol acyltransferase.
12/2006Inhibition of diacylglycerol acyltransferase by alkamides isolated from the fruits of Piper longum and Piper nigrum.

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Hyun Sun Lee Research Topics

Disease

6Obesity
07/2011 - 02/2006
5Type 2 Diabetes Mellitus (MODY)
07/2011 - 12/2006
2Osteoporosis
01/2019 - 01/2017
2Inflammation (Inflammations)
02/2015 - 06/2009
2Metabolic Diseases (Metabolic Disease)
11/2014 - 01/2013
2Insulin Resistance
01/2014 - 12/2013
2Neoplasms (Cancer)
12/2012 - 12/2005
2Atherosclerosis
12/2011 - 01/2005
1Liver Diseases (Liver Disease)
11/2019
1Alcoholic Fatty Liver
02/2017
1Fibrosis (Cirrhosis)
01/2014
1Carcinoma (Carcinomatosis)
01/2014
1Body Weight (Weight, Body)
12/2012
1Vascular Diseases (Vascular Disease)
12/2011
1Chronic Obstructive Pulmonary Disease (COPD)
09/2011
1Asthma (Bronchial Asthma)
06/2009
1Airway Remodeling
06/2009
1Metabolic Syndrome (Dysmetabolic Syndrome X)
11/2008
1Diabetes Mellitus
11/2008
1Hepatocellular Carcinoma (Hepatoma)
11/2008
1Leukemia
09/2007
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
09/2007
1Atherosclerotic Plaque (Atheroma)
04/2007
1Melanoma (Melanoma, Malignant)
06/2005
1Hyperlipidemias (Hyperlipidemia)
02/2005
1Vascular System Injuries
10/2003

Drug/Important Bio-Agent (IBA)

6Diacylglycerol O-AcyltransferaseIBA
11/2014 - 12/2006
5SaponinsIBA
11/2019 - 06/2005
4Triglycerides (Triacylglycerol)IBA
01/2014 - 11/2008
4Pharmaceutical PreparationsIBA
12/2013 - 11/2008
4Acyl Coenzyme A (Acyl CoA)IBA
07/2011 - 12/2006
2platycodin DIBA
01/2019 - 01/2017
2ChangkilIBA
02/2015 - 06/2009
2OvalbuminIBA
02/2015 - 06/2009
2EnzymesIBA
01/2014 - 11/2008
2CholesterolIBA
12/2012 - 02/2005
1platyconic acidIBA
02/2015
1AllergensIBA
02/2015
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2014
1CytokinesIBA
01/2014
1Phospholipids (Phosphatides)FDA LinkGeneric
12/2013
1AcyltransferasesIBA
12/2013
1HDL CholesterolIBA
12/2012
1LDL CholesterolIBA
12/2012
1Becaplermin (PDGF-BB)FDA Link
12/2011
1tangeretinIBA
12/2011
1MucinsIBA
09/2011
1Insulin (Novolin)FDA Link
05/2010
1LeptinIBA
05/2010
1Acetates (Acetic Acid Esters)FDA Link
11/2008
1Glycerol (Glycerine)FDA LinkGeneric
11/2008
1tussilagoneIBA
11/2008
1Imatinib Mesylate (Gleevec)FDA Link
09/2007
1Cholesterol Esters (Cholesteryl Esters)IBA
04/2007
1Lipoproteins (Lipoprotein)IBA
04/2007
1Betulinic AcidIBA
02/2006
1quinone methideIBA
12/2005
1XanthonesIBA
12/2005
1Sterol O-AcyltransferaseIBA
02/2005
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2005
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
01/2005
1Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
01/2005
1E-SelectinIBA
01/2005
1Proteasome InhibitorsIBA
10/2003

Therapy/Procedure

2Therapeutics
06/2009 - 12/2006